Raman Spectroscopic Systems

Raman Spectroscopic Systems

Raman spectroscopic systems provide molecular-level chemical composition insight using Raman scattering, enabling real-time measurement of components in solids, liquids, and gases. A complete Raman system is described as comprising four elements—an analyzer, probes, software, and data analysis—working together to convert raw spectra into usable concentration or quality indicators. This architecture supports deployment as in-line, on-line, or at-line analysis depending on process constraints and required response time.

The key benefit is faster, more specific chemical insight without the delays and sampling risks of offline laboratory workflows. Raman Rxn analyzers are described as configurable up to four channels and available in multiple excitation wavelengths (532 nm, 785 nm, or 1000 nm), with embedded software accessible via touchscreen or web interface. This supports flexible method design and rapid measurement updates as product grades and operating windows change.

Raman probes and optics are central to applying the technique in production environments. The probe portfolio is described as supporting flexible measurement capability (in-line, on-line, or at-line), corrosion-resistant contact materials, and “no-touch and remote measurements,” including non-invasive, non-destructive sampling. Fiber-optic sampling probes are described as enabling chemical analysis of solids, liquids, and gases across installation environments, supporting broad applicability beyond traditional liquid-only analyzers.

Typical applications include chemical and polymer production, oil and gas processing, food and beverage, and pharmaceutical manufacturing, as well as in situ monitoring of bioprocesses such as cell culture, fermentation, and downstream steps. Benefits called out include method transferability from R&D/lab to manufacturing and lab-to-process scalability to “bring chemical analysis from the laboratory to the production environment” for improved quality assurance and process efficiency. Certifications such as CSA, ATEX, and IECEx support deployment where hazardous-area requirements apply.

Implementation success depends on defining the measurement objective (end-point detection, concentration tracking, polymorph identification, solvent ratio control, etc.), selecting probe geometry and materials compatible with the process, and building robust chemometric models where required. With 24/7 connectivity and embedded control software positioned for real-time operation, Raman systems can support continuous verification of reaction progression, tighter batch-to-batch consistency, and earlier detection of deviations—reducing rework, off-spec production, and time-to-decision across complex processes.

Forberg Smith, an exclusive authorized representative of sales and service for Endress+Hauser.